Here we indicate a clinical instance regarding the improvement intrauterine infection of this auditory function as a result of combined medical and medical treatment of someone with all the pituitary macroadenoma, acromegaly and hearing loss.Anamnesis functions someone with an active stage of acromegaly and a pituitary macroadenoma calculating 57x35x32 mm with ante-, supra-, infra-, parasellar scatter, (Knosp III(D), Knosp IV(S) noted a violation of auditory purpose. She was consulted by an otolaryngologist, sensorineural hearing reduction from the right of this third degree had been identified, from the left of the first level. The patient underwent surgical treatment of pituitary adenoma, noted a substantial enhancement in auditory purpose during the early postoperative period. Six months later on, continued audiometry ended up being performed, marked regression of hearing damage ended up being noted.The situation explained by us indicates the reversibility of an unusual complication of acromegaly – hearing loss therefore the need for an interdisciplinary method into the management of patients with this pathology.Functioning pituitary adenomas and pheochromocytomas/paragangliomas are rare within the basic populace. Pituitary adenomas take place in the familial setting in about 5% of instances, whereas pheochromocytomas/paragangliomas may be hereditary in 30-40% of instances. Hereditary syndromes associated with pituitary adenomas include several endocrine neoplasia kinds 1 and 4, familial remote pituitary adenomas, and Carney complex. Hereditary syndromes connected with pheochromocytomas/paragangliomas and genes, mutations in which predispose with their development, are far more many. The initial clinical explanations associated with co-occurrence of pituitary adenoma and pheochromocytoma/paraganglioma within one client time back to the mid twentieth century, but delineating such a co-occurrence into a certain syndrome («3PAs» (pituitary adenoma, pheochromocytoma, paraganglioma)) had been suggested only in 2015. To date, around 100 situations of these a co-occurrence happen explained within the literature. Mutations in genetics encoding subunits of succinate dehydrogenase complex II (SDHx) tend to be revealed into the most of situations, much less common are mutations in MAX, MEN1 plus some various other genes. This analysis summarizes current information on the «3PAs» problem. Hodgkin’s lymphoma (HL) is just one of the most typical malignant lymphoproliferative conditions. Chemotherapy and radiotherapy utilized in the procedure of LH induce a number of toxic effects ultimately causing disorder of urinary system. Hormone disorders in HL and their relationships aided by the therapy used remain becoming clarified. Hypothyroidism (25%), hyperparathyroidism (15.6%) and hypogonadism (29% of men anly suggested.The information suggest a high prevalence regarding the dysfunctions of thyroid, parathyroid glands, and gonads in HL survivors. Assessment for hormonal problems in these customers is strongly suggested.Searching for the aging process tips is amongst the main problems in geriatrics. Increasingly more study in the past few years has been dedicated to the analysis of geroprotective components SS31 , the influence of various conditions and diseases on aging generally speaking. Of certain value could be the dedication of age-related involutive processes in the human body, if they are included in normal ageing or a condition that needs to be fixed to enhance the functioning of body organs and systems. A significant mechanism of aging begins is a change in hormonal activity of endocrine glands, in specific in hormonal activity of thyroid. Frequency of hypothyroidism in advanced age explains relevance associated with the chosen topic. The aim of the analysis would be to find out the role hypothyroidism in aging. The key task was to establish, whether thyroid hormones decline in older age ended up being a protective element Developmental Biology or pathological procedure. Overview of the literary works in the last ten years on subclinical therapy had been completed and then we identified probably the most pressing issues associated with hypothyroidism and aging. We learned information on the relationship between hypothyroidism and significant geriatric syndromes, with special interest compensated to cognitive conditions and psychological disorders.Currently, the procedure of pituitary adenomas is inextricably related to transsphenoidal neurosurgical input. Modern-day technologies found in surgery because of this pituitary pathology, such endoscopy utilizing angled optics, as well as the utilization of specific instruments, sealing and hemostatic products, boost the effectiveness of surgical treatment of pituitary adenomas and minimize the incidence of intraand postoperative problems. The development of radiation types of diagnostics, such as MRI, assists you to much more accurately determine the synthesis of the pituitary gland, assess its dimensions, way of development, and also the amount of intrusion of surrounding tissues. The writers regarding the article described at length the present day technique of transsphenoidal removal of pituitary adenoma using an endoscope. Each phase of this operation is described step-by-step, considering various anatomical features and illustrated. This short article discusses the MRI attributes of pituitary adenomas measurements of the tumor, the direction of their development, the degree of invasion of the cavernous sinuses, the compression influence on the structures regarding the chiasmal-sellar region.